Brad Reisfeld and Arthur Mayeno edited a two-volume book as part of the Humana Press “Methods in Molecular Biology” series entitled “Computational Toxicology”. It is now available from Springer and major bookstores, including amazon.com.
Raymond SH Yang offered a “Physiologically-Based Pharmacokinetic Modeling Workshop for Beginners” at Colorado State University, Fort Collins, Colorado, 06-10 August 2012. See this announcement for more information.
Todd Zurlinden, a graduate student in Brad Reisfeld‘s group, was recently awarded a Science to Achieve Results (STAR) Graduate Student Fellowship from the Environmental Protection Agency. This prestigious award will allow Mr. Zurlinden to pursue research with Dr. Reisfeld in the area of “Environmental Public Health Indicators for Organophosphorus Insecticide Exposure”.
Mike Lyons was awarded a Mentored Quantitative Research Development Award from the National Institutes of Health. This five year, $617,298.00 grant will support development of a project entitled “Optimal Drug Regimens for TB: An Integrated Computational/Experimental Approach”.
The Quantitative and Computation Toxicology (QCT) Research Group at Colorado State University consists of a multidisciplinary team of scientists with an interest in developing and applying rigorous mathematics, computer-based tools, and targeted experimentation to study the effects of toxicants, drugs, and other foreign chemicals on the body.
Members of the group represent a wide variety of disciplines, including toxicology, pathology, biochemistry, chemistry, physics, veterinary medicine, chemical and biological engineering, and biomedical engineering.
Our current members reside at a number of institutions: Colorado State University (Fort Collins, Colorado), The Hamner Institutes for Health Sciences (Research Triangle Park, North Carolina), and the U.S. Environmental Protection Agency (Research Triangle Park, North Carolina).
Owing to their combination of quantitative skills and biomedical research experience, many of our graduates are highly sought after by academia, industry, and government.
There are a number of areas in toxicology of current interest to the group, including studying the toxicities of volatile organic solvents, examining chemically-induced carcinogenesis, developing methodologies for risk assessment, creating techniques for predictive xenobiotic metabolomics, investigating neuro-developmental toxicology and endocrine disruptors, and utilizing state-of-the-art methods to understand toxicological interactions of chemical mixtures.
In general, the focus of research within the group is on developing computational methods and related experimental techniques to study the effects of toxicants, drugs, and other foreign chemicals on the body. Several of the active research areas are listed below.